PrimeRFP SCOUT · Federal Contract Recompete Brief

75N93021C00022Eo14042 - to advance clinical and — Spero Therapeutics, Inc

Spero Therapeutics, Inc holds $23.0M across 2 federal awards, concentrated at Department of Health and Human Services (HHS). This PIID sits alongside 1 related award in the incumbent pipeline. Competition previously drew 23 offers. Set-aside status: NONE. Recompete timing centers on the Dec 31, 2026 PoP end — agencies typically plan 12–18 months ahead.

National Institutes Of Health Niaid
Awarding office
Spero Therapeutics, Inc
Recipient
Dec 31, 2026
PoP end
$8.4M
Obligated
$27M
Potential
541715
NAICS
AN11
PSC
NONE
Set-aside
23 bidders on last award

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Contract facts

NONE
Contract number75N93021C00022
AgencyNational Institutes Of Health Niaid
Awarding officeNational Institutes Of Health Niaid
Awarding agencyDepartment of Health and Human Services (HHS)
Funding agencyDepartment of Health and Human Services (HHS)
IncumbentSpero Therapeutics, Inc
CAGE7SK81
UEINX34PL7NZW24
NAICS541715
PSCAN11
Place of performanceCAMBRIDGE MA
Pricing typeCost Plus Fixed Fee
Extent competedFull And Open Competition
Related solicitationHHS-NIH-NIAID-BAA2020-1
PoP startMay 17, 2021
PoP end (current)Dec 31, 2026
Obligated$8.4M
Current value$10.5M
Potential value$27M

EO14042 - TO ADVANCE CLINICAL AND NON-CLINICAL DEVELOPMENT OF AN ANTIBIOTIC CANDIDATE. is a federal NONE award for National Institutes Of Health Niaid held by Spero Therapeutics, Inc. Estimated value $27M ($8.4M obligated). Current period of performance ends Dec 31, 2026. Last award drew 23 bidders. Place of performance: CAMBRIDGE MA. Related solicitation HHS-NIH-NIAID-BAA2020-1.

EO14042 - TO ADVANCE CLINICAL AND NON-CLINICAL DEVELOPMENT OF AN ANTIBIOTIC CANDIDATE.

Recompete timing

Public
Expiring in 115 days

Current PoP ends Dec 31, 2026 (115 days remaining). Agencies typically plan 12–18 months ahead — at 3.8 months out, that window is already open. The buying decision is likely already in motion.

Incumbent footprint

Public record

Spero Therapeutics, Inc$23.0M obligated across 2 awards (firm-wide, all agencies).

Sole agency: Department of Health and Human Services (HHS)
Department of Health and Human Services (HHS)$23.0M · 100% of firm total
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Related awards

Same incumbent
75A50118C00015
PROVIDE A NCE THROUGH 12/15/2022; INCORPORATE COVID-19 LANGUAGE; UPDATE SOW
$49.8M
Oct 31, 2026

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Frequently asked questions

What is contract 75N93021C00022?

75N93021C00022 (Eo14042 - to advance clinical and) is a National Institutes Of Health Niaid award with a potential value of $27M, currently held by Spero Therapeutics, Inc. Figures are USASpending-sourced public-record facts plus SCOUT recompete analysis.

Which office awarded 75N93021C00022?

National Institutes Of Health Niaid awarded 75N93021C00022 to Spero Therapeutics, Inc (potential $27M).

Who is the incumbent on 75N93021C00022?

Spero Therapeutics, Inc is the incumbent with $23.0M across 2 related awards in SCOUT’s public footprint. The current period of performance ends Dec 31, 2026.

When does Spero Therapeutics, Inc’s 75N93021C00022 come up for recompete?

SCOUT tracks a period-of-performance end of Dec 31, 2026. Actual solicitation timing can shift with extensions, bridges, or consolidations.

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Data: Showing contracts ≥ $100K from federal procurement records (FPDS-NG, SAM.gov, and related repositories), normalized by PrimeRFP SCOUT. Each row keyed by Award ID (PIID); task orders appear as independent rows.

Data as of · refreshed monthlyLatest procurement action
Sources: USASpending, FPDS, SAM.gov · Public-record facts + SCOUT analysis shown above; personalized scoring in SCOUT.
primerfp.com/intel/contract/75N93021C00022