PrimeRFP SCOUT · Federal Contract Recompete Brief

75A50118C00015Provide a NCE through 12 15 — Spero Therapeutics, Inc

Spero Therapeutics, Inc holds $23.0M across 2 federal awards, concentrated at Department of Health and Human Services (HHS). This PIID sits alongside 1 related award in the incumbent pipeline. The prior award was single-bid — competitive dynamics may favor a challenge. Set-aside status: NONE. Recompete timing centers on the Oct 31, 2026 PoP end — agencies typically plan 12–18 months ahead.

Barda - Aspr / Daappo / Barda Dcma

Awarding office

Spero Therapeutics, Inc

Recipient

Oct 31, 2026

PoP end

$31.1M

Obligated

541714

NAICS

AN13

PSC

NONE

Set-aside

1 bidders on last award

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Contract facts

NONE

Contract number75A50118C00015

AgencyBarda - Aspr / Daappo / Barda Dcma

Awarding officeBarda - Aspr / Daappo / Barda Dcma

IncumbentSpero Therapeutics, Inc

UEINX34PL7NZW24

NAICS541714

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PSCAN13

Place of performanceCAMBRIDGE, MA

Related solicitationBAA18100SOL00003

PoP end (current)Oct 31, 2026

Obligated$31.1M

PROVIDE A NCE THROUGH 12/15/2022; INCORPORATE COVID-19 LANGUAGE; UPDATE SOW is a federal NONE award for Barda - Aspr / Daappo / Barda Dcma held by Spero Therapeutics, Inc. Estimated value $49.8M ($31.1M obligated). Current period of performance ends Oct 31, 2026. Last award drew 1 bidder. Place of performance: CAMBRIDGE, MA. Related solicitation BAA18100SOL00003.

PROVIDE A NCE THROUGH 12/15/2022; INCORPORATE COVID-19 LANGUAGE; UPDATE SOW

Recompete timing

Public

● Expiring in 54 days

Current PoP ends Oct 31, 2026 (54 days remaining). Agencies typically plan 12–18 months ahead — at 1.8 months out, that window is already open. The buying decision is likely already in motion.

Incumbent footprint

Public record

Spero Therapeutics, Inc — $23.0M obligated across 2 awards (firm-wide, all agencies).

Sole agency: Department of Health and Human Services (HHS)

Department of Health and Human Services (HHS)$23.0M · 100% of firm total

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Related awards

Same incumbent

75N93021C00022

EO14042 - TO ADVANCE CLINICAL AND NON-CLINICAL DEVELOPMENT OF AN ANTIBIOTIC CANDIDATE.

$10.5M

Dec 31, 2026

Query this award live in SCOUT via MCP — personalized scoring, watchlists, and capture workflow across the corpus. Learn about SCOUT MCP →

Frequently asked questions

What is contract 75A50118C00015?

75A50118C00015 (Provide a NCE through 12 15) is a Barda - Aspr / Daappo / Barda Dcma award with an estimated value of $49.8M, currently held by Spero Therapeutics, Inc. Figures are USASpending-sourced public-record facts plus SCOUT recompete analysis.

Which office awarded 75A50118C00015?

Barda - Aspr / Daappo / Barda Dcma awarded 75A50118C00015 to Spero Therapeutics, Inc.

Who is the incumbent on 75A50118C00015?

Spero Therapeutics, Inc is the incumbent with $23.0M across 2 related awards in SCOUT’s public footprint. The current period of performance ends Oct 31, 2026.

When does Spero Therapeutics, Inc’s 75A50118C00015 come up for recompete?

SCOUT tracks a period-of-performance end of Oct 31, 2026. Actual solicitation timing can shift with extensions, bridges, or consolidations.

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Data: Showing contracts ≥ $100K from federal procurement records (FPDS-NG, SAM.gov, and related repositories), normalized by PrimeRFP SCOUT. Each row keyed by Award ID (PIID); task orders appear as independent rows.

Data as of Aug 20, 2026 · refreshed monthlyLatest procurement action Jul 6, 2026