PrimeRFP SCOUT · Federal Contract Profile

Spero Therapeutics (NX34PL7NZW24)Federal contracts · 2 recompetes

Spero Therapeutics holds $23M in federal volume across 2 award actions, with 100% at Department of Health and Human Services (HHS). SCOUT tracks 2 incumbent recompetes — an estimated $60.3M returning to market over the next 24 months (High exposure). Primary work: Research And Development In (100% prime). Obligations are down 60% year over year.

$23M
Federal Volume
2
Recompetes (24mo)
HHS
Top Agency · 100% firm-wide
2
Award Actions
Small business
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Data through · refreshed monthly · window Sep 2025 – Sep 2026

Why are you looking at Spero Therapeutics?

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What they do

Capability

Service lines

RESEARCH AND DEVELOPMENT IN BIOTECHNOLOGY (EXCEPT NANOBIOTECHNOLOGY) · RESEARCH AND DEVELOPMENT IN THE PHYSICAL, ENGINEERING, AND LIFE SCIENCES (EXCEPT NANOTECHNOLOGY AND BIOTECHNOLOGY) · RESEARCH AND DEVELOPMENT IN THE PHYSICAL, ENGINEERING, AND LIFE SCIENCES (EXCEPT BIOTECHNOLOGY)

Work mix: 100% prime · 0% sub · primary NAICS 541714 / PSC AN13 HEALTH R&D SERVICES; HEALTH CARE SERVICES; EXPERIMENTAL DEVELOPMENT

Where they win

Sole agency
Sole agency: Department of Health and Human Services (HHS)

Recompete exposure: High · 2 in 24mo

Spero Therapeutics has an estimated $60.3M in contracts returning to market over the next 24 months.

Part of the SPERO THERAPEUTICS INC. corporate family · 2 entities
Metrics basis: local_db_api_validated
Recompete exposure & trajectory

Recompete exposure

High

Spero Therapeutics has an estimated $60.3M in contracts returning to market over the next 24 months. 2 within 6 months ($60.3M).

Trajectory
▼ Consolidating-60% YoYFY2025 vs FY2024
'23
'24
'25
“After 35 years in federal contracting, I've seen what separates the firms that win from the ones that wonder why they lost. What SCOUT does is put the kind of competitive and market intelligence in front of BD teams…”
— Shauna Weatherly, FedSubK
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Frequently asked questions

What federal contracts does Spero Therapeutics hold?

Spero Therapeutics (UEI NX34PL7NZW24) shows $23.0M across 2 award actions in SCOUT’s public USASpending-backed profile, with Department of Health and Human Services (HHS) as the top buying agency. Totals cover federal prime awards ≥$100K in the rolling window.

How much in federal contracts does Spero Therapeutics have?

Spero Therapeutics shows $23.0M across 2 award actions. SCOUT tracks 2 incumbent recompetes ($60.3M) returning to market in the next 24 months.

Which agencies does Spero Therapeutics work with?

Spero Therapeutics’s firm-wide obligated mix is led by Department of Health and Human Services (HHS) (100%).

What is the UEI for Spero Therapeutics?

The Unique Entity ID (UEI) for Spero Therapeutics is NX34PL7NZW24.

Does Spero Therapeutics have contracts coming up for recompete?

Yes — SCOUT tracks 2 incumbent recompetes in the next 24 months (High exposure). Open the recompete section on this page for PIID-level timing.

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Data: Showing contracts ≥ $100K from federal procurement records (FPDS-NG, SAM.gov, and related repositories), normalized by PrimeRFP SCOUT. Each row keyed by Award ID (PIID); task orders appear as independent rows.

Sources: USASpending, FPDS, SAM.gov · Data shown is public-record; analysis by PrimeRFP SCOUT. Corpus refreshed Sep 10, 2026. Profile snapshot Aug 19, 2026. · MA
primerfp.com/intel/company/spero-therapeutics-inc